Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Some recent human studies have demonstrated that extracts may help with ankle sprains, knee pain and stiffness, backaches, and mild skin abrasions. We comply with the HONcode standard for trustworthy health information. 2005 - 2023 WebMD LLC. The internal or extensive topical use of comfrey cannot be recommended because of numerous reports of liver damage. The ointment has a very mild herbal fragrance and is soothing on application. Comfrey: ancient and modern uses. Mei N, Guo L, Fu PP, Fuscoe JC, Luan Y, Chen T. Metabolism, genotoxicity, and carcinogenicity of comfrey. Additionally, use on a deep cut may encourage healing of the outer skin the preparation comes in direct contact with faster than the deeper tissue, leading to abscess. #HBTechCareers. Small glass jars with lids for sharing (optional). Comfrey oil is a herbal oil that moisturises skin, and that's been used as a healing herb for a long time. Company number 02758955 Registered VAT number 211727395. Jedlinszki, N., Balzs, B., Csnyi, E., & Csupor, D. (2017). The Pharmaceutical Journal, PJ, December 2007. View abstract. New South Wales Health, Australia. 2010;44(9):637-641. Buy 1 get 1 Half Price on Vitamins & Supplements, Popular Vitamins & Supplements Subscriptions, Buy 1 get 1 Half Price gut health supplements, Guide to sleeping better natural sleeping remedies, Living in the now, gut health & mental wellbeing, The thing that makes you different makes you special, Bhupesh Panchal, Senior Regulatory Affairs Associate, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908267/, http://www.missouribotanicalgarden.org/PlantFinder/PlantFinderDetails.aspx, http://www.sciencedirect.com/science/article/pii/S0965229913001672, http://www.ncbi.nlm.nih.gov/pubmed/22887778, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363250/, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6631335/, https://pubmed.ncbi.nlm.nih.gov/22887778/, https://www.ema.europa.eu/en/documents/herbal-report/final-assessment-report-symphytum-officinale-l-radix_en.pdf, http://pennstatehershey.adam.com/content.aspx?productid=107&pid=33&gid=000234. Limited trials have evaluated the effectiveness of alkaloid-free preparations for external use; however, these studies did not examine how much liver damage occurred in patients. How do you use it and are there any side effects? Centurian, South Africa: Medpharm Scientific Publishers. After 7 years in this role and a further year working as a drug safety officer in the pharmaceutical industry, Bhupesh joined Holland &Barrett as a Senior Regulatory Affairs Associate in 2019. Published 2021 Sep 20. doi:10.1590/1519-6984.249209, Frost R, MacPherson H, O'Meara S. A critical scoping review of external uses of comfrey (Symphytum spp.). Lorem ipsum dolor sit nulla or narjusto laoreet onse ctetur adipisci. In a double-blind, randomized, placebo-controlled study involving 120 patients with acute back pain, symptoms were quickly reduced in the group using 4 grams of an ointment containing 35% comfrey root extract 3x/day for 5 days (Giannetti et al., 2010). Megan Nunn, PharmD, is a community pharmacist in Tennessee with over twelve years of experience in medication counseling and immunization. View abstract. Documented adverse effects (the pyrrolizidine alkaloids, have substantial risk of causing fatal liver damage and can cause abortion). Taking comfrey along with a medication that can harm the liver might increase the risk of liver damage. Effect of a blend of comfrey root extract (Symphytum officinale L.) and tannic acid creams in the treatment of osteoarthritis of the knee: randomized, placebo-controlled, double-blind, multiclinical trials. All Technology Jobs. This site uses cookies to improve your experience. Undergoingmassage or taking up yoga may help alleviate pain and help people with back or joint problems function more easily. Label with the ingredients and date made. Sowa I, Paduch R, Strzemski M, et al. Generic name: comfrey [COM-free] This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Browse our Sports Hub, Get 20% student discount with Student Beans, Discover the latest natural beauty products, Buy 1 get 1 Half Price on Vitamins & Supplements, Popular Vitamins & Supplements Subscriptions, Buy 1 get 1 Half Price gut health supplements, Guide to sleeping better natural sleeping remedies, Living in the now, gut health & mental wellbeing, The thing that makes you different makes you special, For the symptomatic relief of minor sprains and bruises, Contains Comfrey which is known for its healing properties. No comments. Eucalyptus oil is used externally to stimulate blood flow. When the root is boiled in water, it forms a sticky, glue-like paste. Dietary supplements are not regulated like drugs in the United States, meaning the Food and Drug Administration (FDA) does not approve them for safety and effectiveness before products are marketed. Finally, well warn of any side effects associated with comfrey oil. hollandandbarrett.com is a trading name of Holland & Barrett Retail Limited,. Comfrey is an herb in the Boraginaceae family and has small purple flowers. 2008;54(1):7-20. Avila C, Breakspear I, Hawrelak J, Salmond S, Evans S. A systematic review and quality assessment of case reports of adverse events for borage (Borago officinalis), coltsfoot (Tussilago farfara) and comfrey (Symphytum officinale). We go to great efforts to ensure that the information on this page is accurate at the time that the page was last edited. Roeder E. Medicinal plants in Europe containing pyrrolizidine alkaloids. Wang YP, Yan J, Fu PP, Chou MW. After testing their 1000mg CBD oil drops for over a month, we now have little question this is the best CBD oil within the UK as of 2019. Comfrey ( Symphytum officinale) is an attractive ornamental plant used in gardening and medicine. Comfrey cream may help treat knee osteoarthritis, according to a Cochrane review of topical herbal therapies. Comfrey may be used topically as a cream, ointment, salve, or paste. Tanret, I. and Duh, D. [Pharmaceutical sheet. This is because only a small amount of the pyrrolizidine alkaloids are absorbed through the skin (. 2013;27(6):811-7. 2011;10(3):147-56. View abstract. Complement Ther Clin Pract. 1 Since at least the 4 th century, people have used comfrey medicinally. Predel, H. G., Giannetti, B., Koll, R., Bulitta, M., & Staiger, C. (2005). Drugs and Lactation Database (LactMed). Complement Ther Med. Thank you, {{form.email}}, for signing up. Other prescription medicines that may harm the liver include: Some supplements may also harm the liver, including: It is essential to carefully read a supplement's ingredient list and nutrition facts panel to know which ingredients and how much of each ingredient is included. Comfreycontains PAs, substances that can cause significant damage, including: Therefore, it should never be taken by mouth. Comfrey [Online article]. Topically, comfrey root and leaf extracts have been traditionally used for bruises, sore muscles and joints, sprains, mild wounds, and gout (Natural Medicines, 2020). Koll, R., Buhr, M., Dieter, R., Pabst, H., Predel, H. G., Petrowicz, O., & Staiger, C. (2004). Information from this source is evidence-based and objective, and without commercial influence. These side effects may be common or severe. Herbal/health supplements should be purchased from a reliable source to minimize the risk of contamination. 2013;5(5):CD010538. With extract of Comfrey. Influence of moderate physical exertion on subacute low back pain, after Symphytum officinale ointment treatment. Two interesting studies found that a topical application of a product containing comfrey root extract helped with knee pain and stiffness. Be sure to use comfrey root from a reputable source that has properly identified the species. Arzneimittelforschung. Therapeutic Research Faculty 2020. It's typically only used in small amounts for a very short period. It produces clusters of purple, blue, and white flowers, and it's famous for its long . Brassica Campest is Seed Oil (Rapeseed Oil), Symphytum Officinale Herb (Comfrey Herb), BHA, Eucalyptus Globulus Leaf Oil (Eucalyptus Oil). All rights reserved. Transfer the cooled oil and butter mixture to a standing electric mixer or blender. View abstract. They help us to understand how people use the website and give us the ability to provide targeted marketing to you. Phytomedicine. Complementary Health Approaches for Chronic Pain: What the Science Says. Hybrids and other species may have a similar appearance but could have significantly different amounts of the toxic pyrrolizidine alkaloids (Kucera et al., 2018). Choose a supplement tested by a trusted third party, such as USP, ConsumerLabs, or NSF when possible. Treatment with 4Jointz reduces knee pain over 12 weeks of treatment in patients with clinical knee osteoarthritis: a randomised controlled trial. Can a comfrey (Symphytum officianale) root extraction help ease aching joints and muscles? The Comfrey Ointment that I have been using is to be used only for sprains and bruises. Scoop the finished comfrey cream into sanitized glass jars. Although topical comfrey has been used for this indication, there's little evidence that it helps and can pose a big risk for nursing babies. What Are the Side Effects of Comfrey Cream? Pyrrolizidine alkaloids are very toxic to the liver and are also carcinogenic (cause cancer). Comfrey also is known as Russian comfrey, knitbone, radix consolidate, bruisewort, blackwort, and slippery root. Additionally, because its alkaloids are absorbed through the skin, use of comfrey as a poultice should not exceed an exposure of 100 mcg/day of the alkaloids. Please read the Topical Use Safety section of this article (above) before using. Laslett, L. L., Quinn, S. J., Darian-Smith, E., Kwok, M., Fedorova, T., Korner, H., Steels, E., March, L., and Jones, G. Treatment with 4Jointz reduces knee pain over 12 weeks of treatment in patients with clinical knee osteoarthritis: a randomised controlled trial. This perennial can grow up to 4-feet tall. 2011;10(3):147-56. doi:10.1016/j.jcm.2011.01.003, Laslett LL, Quinn SJ, Darian-Smith E, et al. Beth Thomas, PharmD, is a clinical pharmacist and founder of BMT Consulting Services, LLC. 98% Naturally derived. Regulatory Toxicology and Pharmacology, 83, 1-4. https://doi.org/10.1016/j.yrtph.2016.11.015. radix) extract ointment in the treatment of patients with painful osteoarthritis of the knee: results of a double-blind, randomised, bicenter, placebo-controlled trial. Barna, M., Kucera, A., Hladikova, M., & Kucera, M. (2012). randomized double-blind study of 278 patients with fresh abrasions, a. topical preparation containing a 10% comfrey leaf extraction applied for 2-3 days reduced wound healing time of adults and children without side effects (Barna et al., 2012). Stickel F, Seitz HK. An Evidence-Based Reference. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. HTB; 2021 2; Youtube; Twitter; Facebook; ; . While larger and more studies are needed to fully determine safety and effectiveness, short term topical application of comfrey may give you peace of mind, relief, and support while you rest and heal, following any additional advice from your physician. Bagheri Z, Azizi A, Oshvandi K, Mohammadi Y, Larki-Harchegani A. For one of these studies, the average time participants had experienced knee pain and stiffness leading up to the study was six and a half years! This perennial can grow up to 4-feet tall. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use. (3), 147-156. https://doi.org/10.1016/j.jcm.2011.01.003. A limited number of clinical trials show short-term efficacy of topically applied, alkaloid-free comfrey preparations in skin abrasions and inflammatory conditions. Supplement use should be individualized and vetted by a healthcare professional, such as a registered dietician, pharmacist, or healthcare provider. The herbal topical cream was prepared at two different strengths, as an additional measure of efficacy. Herbal drugs and phytopharmaceuticals. Be sure to choose organic carrier oils and essential oils when possible. Herb & Supplement Guide. View abstract. 4-4-2009;139(13-14):210-211. Many of those following the folk use of comfrey up to present-day think so. 2013;21(6):724-45. This is not a complete list of side effects and others may occur. View abstract. As we are constantly reviewing and developing our products to meet our consumer needs, consumers, particularly those that suffer from allergies and intolerances, should always check product labelling, warnings, and directions provided with the product that is delivered, prior to use or consumption. Check regularly, but it should take about six weeks for all the leaves to break down into a thick, black liquid. Potters Herbal Comfrey Oil is a soothing aromatic herbal massage oil. Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Bird Flu Deaths Prompt U.S. to Test Vaccine in Poultry, COVID Treatment in Development Appears Promising, Marriage May Help Keep Your Blood Sugar in Check, Getting Outdoors Might Help You Take Fewer Meds, New Book: Take Control of Your Heart Disease Risk, Getting Help for a Loved One With Psychosis: It's Complicated, Health News and Information, Delivered to Your Inbox, Vitamins and Supplements to Avoid with Hepatitis C. Complementary Health Approaches for Chronic Pain: What the Science Says. Kucera, M., Barna, M., Horacek, O., Kovarikova, J., and Kucera, A. Efficacy and safety of topically applied Symphytum herb extract cream in the treatment of ankle distortion: results of a randomized controlled clinical double blind study. Comfrey contains chemicals that cause serious liver damage when taken by mouth. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. J Toxicol Environ Health B Crit Rev. More research is needed. Comfrey is changed and broken down by the liver. Credit Solution Experts Incorporated offers quality business credit building services, which includes an easy step-by-step system designed for helping clients build their business credit effortlessly. J Pain. Mackinnon, M. In general practice, 'always expect the unexpected'. randomized, placebo-controlled, double-blind, multi-clinical trial.
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